Gene and Protein Information
class A G protein-coupled receptor
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	7	470	11q13.2	GPR152	G protein-coupled receptor 152
Mouse	7	511	19 A	Ackr5	atypical chemokine receptor 5
Rat	7	394	1q42	Gpr152	G protein-coupled receptor 152

Previous and Unofficial Names

PGR1 | PGR5 | G-protein coupled receptor PGR5 | Gpr152

Database Links
Specialist databases
GPCRdb	gp152_human (Hs), gp152_mouse (Mm)
Other databases
Alphafold	Q8TDT2 (Hs), Q8BXS7 (Mm)
ChEMBL Target	CHEMBL4523900 (Hs)
Ensembl Gene	ENSG00000175514 (Hs), ENSMUSG00000044724 (Mm), ENSRNOG00000021912 (Rn)
Entrez Gene	390212 (Hs), 269053 (Mm), 688884 (Rn)
Human Protein Atlas	ENSG00000175514 (Hs)
KEGG Gene	hsa:390212 (Hs), mmu:269053 (Mm), rno:688884 (Rn)
Pharos	Q8TDT2 (Hs)
RefSeq Nucleotide	NM_206997 (Hs), NM_206973 (Mm), XM_001068698 (Rn)
RefSeq Protein	NP_996880 (Hs), NP_996856 (Mm), XP_001068698 (Rn)
UniProtKB	Q8TDT2 (Hs), Q8BXS7 (Mm)
Wikipedia	GPR152 (Hs)

Expression Datasets
Show »« Hide Log average relative transcript abundance in mouse tissues measured by qPCR from Regard, J.B., Sato, I.T., and Coughlin, S.R. (2008). Anatomical profiling of G protein-coupled receptor expression. Cell, 135(3): 561-71. [PMID:18984166] [Raw data: website] There should be a chart of expression data here, you may need to enable JavaScript!

Biologically Significant Variants
Type:  Single nucleotide polymorphism Species:  Human Amino acid change:  L317V Global MAF (%):  9 Subpopulation MAF (%):  AFR|AMR: 39|2 Minor allele count:  C=0.093/204 SNP accession:  VAR_059323, rs1638559 Validation:  1000 Genomes, Frequency
Type:  Single nucleotide polymorphism Species:  Human Amino acid change:  G61R Global MAF (%):  5 Subpopulation MAF (%):  AMR|ASN: 1|19 Minor allele count:  T=0.054/118 SNP accession:  rs79423227 Validation:  1000 Genomes, Frequency

General Comments
GPR152 is found to be most closely related to the gamma-group of Rhodopsin family [1].