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Vesicular nucleotide transporter C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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The vesicular nucleotide transporter is the most recent member of the SLC17 family to have an assigned function. Uptake of ATP was independent of pH, but dependent on chloride ions and membrane potential [2].

Transporters

1010
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Targets of relevance to immunopharmacology are highlighted in blue

VNUT (Vesicular nucleotide transporter / SLC17A9) C Show summary »


Target Id 1010
Nomenclature Vesicular nucleotide transporter
Systematic nomenclature SLC17A9
Common abbreviation VNUT
Previous and unofficial names solute carrier family 17 member 9 | solute carrier family 17 (vesicular nucleotide transporter), member 9 | solute carrier family 17
Genes SLC17A9 (Hs), Slc17a9 (Mm), Slc17a9 (Rn)
Ensembl ID ENSG00000101194 (Hs), ENSMUSG00000023393 (Mm), ENSRNOG00000010275 (Rn)
UniProtKB AC Q9BYT1 (Hs), Q8VCL5 (Mm)
Bioparadigms SLC Tables SLC17A9 (Hs)
RESOLUTE SLC17A9 (Hs)
Endogenous substrates
ATP [2]
guanosine-5'-triphosphate [2]
guanosine 5'-diphosphate [2]
Selective inhibitors
clodronic acid pIC50 7.8 [1]
Stoichiometry Unknown

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How to cite this family page

Database page citation:

Vesicular nucleotide transporter. Accessed on 25/04/2024. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=192.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Transporters. Br J Pharmacol. 180 Suppl 2:S374-469.