Gene and Protein Information
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	37	2752	18p11.22-p11.21	PIEZO2	piezo type mechanosensitive ion channel component 2
Mouse	37	2822	18 E1	Piezo2	piezo-type mechanosensitive ion channel component 2
Rat	-	2720	18q12.1	Piezo2	piezo-type mechanosensitive ion channel component 2
Gene and Protein Information Comments
Piezo proteins have between 24 and 36 predicted transmembrane domains.

Previous and Unofficial Names

DA3 | DA5 | DAIPT | FAM38B | FAM38B2 | HsT748 | HsT771 | MWKS

Database Links
Alphafold	Q9H5I5 (Hs), Q8CD54 (Mm)
CATH/Gene3D	1.25.10.10
Ensembl Gene	ENSG00000154864 (Hs), ENSMUSG00000041482 (Mm), ENSRNOG00000038784 (Rn)
Entrez Gene	63895 (Hs), 667742 (Mm), 307380 (Rn)
Human Protein Atlas	ENSG00000154864 (Hs)
KEGG Gene	hsa:63895 (Hs), mmu:667742 (Mm), rno:307380 (Rn)
OMIM	613629 (Hs)
Orphanet	ORPHA332055 (Hs)
Pharos	Q9H5I5 (Hs)
RefSeq Nucleotide	NM_022068 (Hs), NM_001039485 (Mm)
RefSeq Protein	NP_071351 (Hs), NP_001034574 (Mm)
UniProtKB	Q9H5I5 (Hs), Q8CD54 (Mm)
Wikipedia	PIEZO2 (Hs)

Functional Characteristics
Mechano-activated

Physiological Functions
Mediates vasomotion-triggered cluster firings in dorsal root ganglion neurons which triggers episodic neuropathic pain. Species:  Mouse Tissue:  References:  1