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IFN-β1b (recombinant human)   Click here for help

GtoPdb Ligand ID: 8340

Synonyms: Betaferon® | Betaseron® | Extavia® | IFNb1b
Approved drug Immunopharmacology Ligand
IFN-β1b (recombinant human) is an approved drug (FDA (1993), EMA (1995))
Compound class: Peptide
Comment: Compared to the sequence of endogenous IFN-β, IFN-β1b has a Ser to Cys substitution at position 17, but does not retain the glycosylation site at Asn80. It also lacks the initiating Met. This recombinant peptide is produced in E.coli.
Immunopharmacology Disease
Disease X-Refs Comment References
Multiple sclerosis Disease Ontology: DOID:2377
OMIM: 126200
Orphanet: ORPHA802
 Approved drug for relapsing forms of MS.