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IFN-β1a (recombinant human)   Click here for help

GtoPdb Ligand ID: 8339

Synonyms: Avonex® | Rebif®
Approved drug
IFN-β1a (recombinant human) is an approved drug (FDA (1996), EMA (1997))
Compound class: Peptide
Comment: Compared to the sequence of the endogenous peptide, IFN-β1a has a Gln to Cys substitution at position 17 and retains the Asn glycosylation site at position 80. Whilst the regular form of this peptide has to be injected 1-3 times/week, a PEGylated form (peginterferon beta-1a) is now available that requires less frequent administration (on a fortnightly basis).
Classification Click here for help
Compound class Peptide
Approved drug? Yes. EU EMA (1997)  |  US FDA (1996)
International Nonproprietary Names Click here for help
INN number INN
5380 interferon beta
Synonyms Click here for help
Avonex® | Rebif®
Database Links Click here for help
DrugBank Ligand DB00060
GtoPdb PubChem SID 252166551
Search PubMed clinical trials interferon beta
Search PubMed titles interferon beta
Search PubMed titles/abstracts interferon beta
Wikipedia Interferon_beta_1a