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Synonyms: Myalept® | r-metHuLeptin | R-methuleptin
metreleptin is an approved drug (FDA (2014), EMA (2018))
Compound class:
Peptide
Comment: Metreleptin is a recombinant, 147 amino acid (~16kDa), N-methionyl- analogue of human leptin [1]. Leptin is an adipokine (cytokine secreted by adipose tissue).
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Classification ![]() |
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| Compound class | Peptide |
| Approved drug? | Yes. EU EMA (2018) | US FDA (2014) |
International Nonproprietary Names ![]() |
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| INN number | INN |
| 7808 | metreleptin |
Synonyms ![]() |
| Myalept® | r-metHuLeptin | R-methuleptin |
Database Links ![]() |
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| CAS Registry No. | 186018-45-1 |
| ChEMBL Ligand | CHEMBL2107857 |
| GtoPdb PubChem SID | 178103905 |
| Search PubMed clinical trials | metreleptin |
| Search PubMed titles | metreleptin |
| Search PubMed titles/abstracts | metreleptin |
| Wikipedia | Metreleptin |