GtoPdb is requesting financial support from commercial users. Please see our sustainability page for more information.
| 
                                                                Synonyms: drotrecogin alfa (activated) | HSDB 7366 | Xigris®
                                 drotrecogin alfa is an approved drug (FDA (2001), EMA (2009)) Compound class: 
                                                            Peptide
                                 
                                    
                                        Comment: Drotrecogin alfa (activated) is a recombinant form of human activated protein C.
                                    
                                 | 
| Bioactivity Comments | 
| The molecular mechanism is complex and includes inhibition of coagulation factors Va and VIIIa, but we have been unable to find peer reviewed data to substantiate the molecular interaction. | 
| Selectivity at enzymes | |||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Key to terms and symbols | Click column headers to sort | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
| 
 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||