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parawixin 1   Click here for help

GtoPdb Ligand ID: 5352

Synonyms: PbTx1
Compound class: Natural product
Comment: Parawixin 1 is a bioactive HPLC-derived fraction of the toxin isolated from the venom of the spider Parawixia bistriata It is a mixture of complex organic compounds. Discrete active substances in Parawixin 1 are yet to be fully resolved [2].
Mechanism of action includes enhanced glutamate transport via activation of excitatory amino acid transporter 2 (EAAT2) in the brain [1].
Ligand mentioned in the following text fields
Glutamate transporter subfamily comments