Abbreviated name: DHA
Synonyms: all-cis-DHA | all-cis-docosa-4,7,10,13,16,19-hexaenoic acid | doconexent | Omega 3 fatty acid | Omega-3 marine triglycerides | Retriacyl® (proposed trade name)
Compound class:
Metabolite
Comment: Docosahexaenoic acid is an endogenous omega-3 fatty acid, activating all 3 retinoid X receptor isoforms. It has no activity at retinoic acid receptors (RARs), the thyroid hormone receptor or the vitamin D receptor (VDR).
Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
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Classification | |
Compound class | Metabolite |
IUPAC Name |
(4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoic acid |
International Nonproprietary Names | |
INN number | INN |
6428 | doconexent |
Synonyms |
all-cis-DHA | all-cis-docosa-4,7,10,13,16,19-hexaenoic acid | doconexent | Omega 3 fatty acid | Omega-3 marine triglycerides | Retriacyl® (proposed trade name) |
Database Links | |
Specialist databases | |
GPCRdb Ligand | docosahexaenoic acid |
Other databases | |
CAS Registry No. | 6217-54-5 (source: Scifinder) |
ChEBI | CHEBI:28125 |
ChEMBL Ligand | CHEMBL367149 |
DrugCentral Ligand | 4289 |
GtoPdb PubChem SID | 135651477 |
LIPID MAPS | LMFA01030185 |
PubChem CID | 445580 |
RCSB PDB Ligand | HXA |
Search Google for chemical match using the InChIKey | MBMBGCFOFBJSGT-KUBAVDMBSA-N |
Search Google for chemicals with the same backbone | MBMBGCFOFBJSGT |
Search PubMed clinical trials | doconexent |
Search PubMed titles | doconexent |
Search PubMed titles/abstracts | doconexent |
UniChem Compound Search for chemical match using the InChIKey | MBMBGCFOFBJSGT-KUBAVDMBSA-N |
UniChem Connectivity Search for chemical match using the InChIKey | MBMBGCFOFBJSGT-KUBAVDMBSA-N |
Wikipedia | Docosahexaenoic_acid |
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Docosahexaenoic acid (links to external site)
Cat. No. 3687 |