mambalgin-1

Ligand id: 10308

Name: mambalgin-1

Classification
Compound class Peptide or derivative
Comments
Mambalgin-1 is a polypeptide component of the venom from the black mamba (Dendroaspis polylepis polylepis) [2]. Mambalgin-2 has also been identified and this differs from Mambalgin-1 by only one amino acid at residue 4 of the mature peptide (Tyr replaced by Phe in Mambaglin-2) [2]. These Mambalgin peptides have been shown to block acid-sensing ion channels, principally ASIC1a- and ASIC1b-containing channels [1-2].
Database Links
GtoPdb PubChem SID 381744989
UniProtKB P0DKR6 (Dpp)