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Forkhead box TFs

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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Forkhead box transcription factors are important regulators of the expression of genes involved in cell growth, proliferation, differentiation, and longevity, and are important during embryonic development. They bind DNA via a conserved DNA-binding module known as the forkhead domain.

Targets

Targets of relevance to immunopharmacology are highlighted in blue

forkhead box N1 Show summary » More detailed page

How to cite this family page

Database page citation:

Forkhead box TFs. Accessed on 17/11/2019. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=974.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Buneman OP, Cidlowski JA, Christopoulos A, Davenport AP, Fabbro D, Spedding M, Striessnig J, Davies JA; CGTP Collaborators. (2019) The Concise Guide to PHARMACOLOGY 2019/20: Introduction and Other Protein Targets. Br J Pharmacol. 176 Issue S1: S1-S20.