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EF-hand domain containing proteins

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).


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The EF hand is conserved structural domain that is found in a large family of calcium-binding proteins. It is formed by two alpha helices linked by a short loop region.


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Targets of relevance to immunopharmacology are highlighted in blue

nucleobindin 1 Show summary »

RAS guanyl releasing protein 1 Show summary » More detailed page go icon to follow link

S100 calcium binding protein A11 / S100A11 Show summary » More detailed page go icon to follow link


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How to cite this family page

Database page citation:

EF-hand domain containing proteins. Accessed on 25/07/2024. IUPHAR/BPS Guide to PHARMACOLOGY,

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Buneman OP, Faccenda E, Harding SD, Spedding M, Cidlowski JA, Fabbro D, Davenport AP, Striessnig J, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Introduction and Other Protein Targets. Br J Pharmacol. 180 Suppl 2:S1-22.