Top ▲

Notch receptors C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

Click here for help

« Hide More detailed introduction go icon to follow link

Aberrant Notch signalling is implicated in a number of human cancers [7,12,14,17], and there is intense pharmaceutical activity being directed towards achieving clinically effective Notch pathway inhibition [3,10].

Targets

Click here for help

Targets of relevance to immunopharmacology are highlighted in blue

notch receptor 1 C Show summary » More detailed page go icon to follow link

notch receptor 2 C Show summary » More detailed page go icon to follow link

notch receptor 3 C Show summary » More detailed page go icon to follow link

notch receptor 4 C Show summary »

Further reading

Click here for help

Show »

References

Click here for help

Show »

NC-IUPHAR subcommittee and family contributors

Show »

How to cite this family page

Database page citation (select format):

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Buneman OP, Cidlowski JA, Christopoulos A, Davenport AP, Fabbro D, Spedding M, Striessnig J, Davies JA; CGTP Collaborators. (2019) The Concise Guide to PHARMACOLOGY 2019/20: Introduction and Other Protein Targets. Br J Pharmacol. 176 Issue S1: S1-S20.