Top ▲ Lysyl oxidases

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).


Click here for help

« Hide

Lysyl oxidases are extracellular enzymes that are vital for cross-linking fibrillar elastin and collagens and for extracellular matrix stabilisation [2,5,5]. LOX and LOXL2 are implicated in fibrosis, tumourigenesis, and metastasis [1], and are subsequently molecular targets for cancer drug discovery [6].


Click here for help

Targets of relevance to immunopharmacology are highlighted in blue

lysyl oxidase Show summary » More detailed page go icon to follow link

lysyl oxidase like 2 Show summary » More detailed page go icon to follow link


Click here for help

Show »

How to cite this family page

Database page citation: Lysyl oxidases. Accessed on 25/04/2024. IUPHAR/BPS Guide to PHARMACOLOGY,

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Enzymes. Br J Pharmacol. 180 Suppl 2:S289-373.