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Carbonic anhydrases C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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Carbonic anhydrases facilitate the interconversion of water and carbon dioxide to bicarbonate ions and protons (EC 4.2.1.1), with over a dozen gene products identified in man. The enzymes function in acid-base balance and the movement of carbon dioxide and water. They are targetted for therapeutic gain by particular antiglaucoma agents and diuretics.

Enzymes

Targets of relevance to immunopharmacology are highlighted in blue

CA I (carbonic anhydrase 1) C Show summary » More detailed page

CA II (carbonic anhydrase 2) Show summary » More detailed page

CA IV (carbonic anhydrase 4) Show summary » More detailed page

CA VA (carbonic anhydrase 5A) Show summary » More detailed page

CA VII (carbonic anhydrase 7) C Show summary » More detailed page

CA IX (carbonic anhydrase 9) Show summary » More detailed page

CA XII (carbonic anhydrase 12) C Show summary » More detailed page

CA XIII (carbonic anhydrase 13) C Show summary » More detailed page

CA XIV (carbonic anhydrase 14) C Show summary » More detailed page

Further reading

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References

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How to cite this family page

Database page citation:

Carbonic anhydrases. Accessed on 13/10/2019. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=842.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Marrion NV, Peters JA, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. (2017) The Concise Guide to PHARMACOLOGY 2017/18: Enzymes. Br J Pharmacol. 174 Suppl 1: S272-S359.