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Type IX RTKs: MuSK C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).


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The muscle-specific kinase MuSK is associated with the formation and organisation of the neuromuscular junction from the skeletal muscle side. Agrin (AGRN, O00468) forms a complex with low-density lipoprotein receptor-related protein 4 (LRP4, O75096) to activate MuSK [1].


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Targets of relevance to immunopharmacology are highlighted in blue

MuSK (muscle associated receptor tyrosine kinase) C Show summary » More detailed page go icon to follow link


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How to cite this family page

Database page citation:

Type IX RTKs: MuSK. Accessed on 25/07/2024. IUPHAR/BPS Guide to PHARMACOLOGY,

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Catalytic receptors. Br J Pharmacol. 180 Suppl 2:S241-288.