Type VI RTKs: PTK7/CCK4 | Catalytic receptors | IUPHAR/BPS Guide to IMMUNOPHARMACOLOGY

Type VI RTKs: PTK7/CCK4 C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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The PTK7 receptor is associated with polarization of epithelial cells and the development of neural structures. Sequence analysis suggests that the gene product is catalytically inactive as a protein kinase, although there is evidence for a role in Wnt signalling [1].

Receptors

Targets of relevance to immunopharmacology are highlighted in blue

CCK4 (protein tyrosine kinase 7 (inactive)) C Show summary »« Hide summary More detailed page go icon to follow link

Target Id

1848

Nomenclature

protein tyrosine kinase 7 (inactive)

Common abbreviation

CCK4

Previous and unofficial names

serum response factor | Srf | chz | protein tyrosine kinase 7

Genes

PTK7 (Hs), Ptk7 (Mm), Ptk7 (Rn)

Ensembl ID

ENSG00000112655 (Hs), ENSMUSG00000023972 (Mm), ENSRNOG00000039976 (Rn)

UniProtKB AC

Q13308 (Hs), Q8BKG3 (Mm)

EC number

2.7.10.1

Comments

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References

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How to cite this family page

Database page citation:

Type VI RTKs: PTK7/CCK4. Accessed on 08/10/2024. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=792.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Catalytic receptors. Br J Pharmacol. 180 Suppl 2:S241-288.