Top ▲

Type II PIP kinases (1-phosphatidylinositol-5-phosphate 4-kinase family)

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

Click here for help

« Hide

Type II PIP kinases are essential for the production of the second messenger phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) by phosphorylating PtdIns(5)P [1]. This enzyme family is also known as type II PIP(5)Ks.

Enzymes

Click here for help

Targets of relevance to immunopharmacology are highlighted in blue

PIP4K2A (phosphatidylinositol-5-phosphate 4-kinase type 2 alpha) C Show summary » More detailed page go icon to follow link

PIP4K2B (phosphatidylinositol-5-phosphate 4-kinase type 2 beta) C Show summary » More detailed page go icon to follow link

PIP4K2C (phosphatidylinositol-5-phosphate 4-kinase type 2 gamma) C Show summary » More detailed page go icon to follow link

References

Click here for help

Show »

How to cite this family page

Database page citation:

Type II PIP kinases (1-phosphatidylinositol-5-phosphate 4-kinase family). Accessed on 04/11/2024. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=674.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Enzymes. Br J Pharmacol. 180 Suppl 2:S289-373.