Top ▲

Vasopressin and oxytocin receptors C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).


« Hide More detailed introduction

Vasopressin (AVP) and oxytocin (OT) receptors (nomenclature as recommended by NC-IUPHAR [20]) are activated by the endogenous cyclic nonapeptides vasopressin (AVP, P01185) and oxytocin (OXT, P01178). These peptides are derived from precursors which also produce neurophysins (neurophysin I for oxytocin; neurophysin II for vasopressin). Vasopressin and oxytocin differ at only 2 amino acids (positions 3 and 8). There are metabolites of these neuropeptides that may be biologically active [16].


Targets of relevance to immunopharmacology are highlighted in blue

V1A receptor C Show summary » More detailed page

V1B receptor C Show summary » More detailed page

V2 receptor C Show summary » More detailed page

OT receptor C Show summary » More detailed page


Show »

Further reading

Show »


Show »

NC-IUPHAR subcommittee and family contributors

Show »

How to cite this family page

Database page citation:

Stephen Lolait, Daniel Bichet, Michel Bouvier, Bice Chini, Gerald Gimpl, Gilles Guillon, Tadashi Kimura, Mark Knepper, Maurice Manning, Bernard Mouillac, Anne-Marie O'Carroll, Claudine Serradeil-Le Gal, Melvyn Soloff, Joseph G. Verbalis, Mark Wheatley, Hans H. Zingg. Vasopressin and oxytocin receptors. Accessed on 19/08/2019. IUPHAR/BPS Guide to PHARMACOLOGY,

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Christopoulos A, Davenport AP, Kelly E, Marrion NV, Peters JA, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. (2017) The Concise Guide to PHARMACOLOGY 2017/18: G protein-coupled receptors. Br J Pharmacol. 174 Suppl 1: S17-S129.