Wnk family

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Enzymes

Targets of relevance to immunopharmacology are highlighted in blue

WNK1 (WNK lysine deficient protein kinase 1) Show summary »« Hide summary More detailed page go icon to follow link

Target Id

2280

Nomenclature

WNK lysine deficient protein kinase 1

Common abbreviation

WNK1

Previous and unofficial names

hereditary sensory neuropathy, type II | Hsn2 | prkwnk1

Genes

WNK1 (Hs), Wnk1 (Mm), Wnk1 (Rn)

Ensembl ID

ENSG00000060237 (Hs), ENSMUSG00000045962 (Mm), ENSRNOG00000009956 (Rn)

UniProtKB AC

Q9H4A3 (Hs), P83741 (Mm), Q9JIH7 (Rn)

EC number

2.7.11.1

Inhibitors

PP1 pK_i 4.9 [2]

WNK2 (WNK lysine deficient protein kinase 2) Show summary »« Hide summary More detailed page go icon to follow link

WNK3 (WNK lysine deficient protein kinase 3) Show summary »« Hide summary More detailed page go icon to follow link

WNK4 (WNK lysine deficient protein kinase 4) Show summary »« Hide summary More detailed page go icon to follow link

References

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How to cite this family page

Database page citation:

Wnk family. Accessed on 24/04/2024. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=643.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Enzymes. Br J Pharmacol. 180 Suppl 2:S289-373.