Trbl family

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Kinases (EC 2.7.x.x)
CAMK: Calcium/calmodulin-dependent protein kinases
Trbl family

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Enzymes

Targets of relevance to immunopharmacology are highlighted in blue

TRB1 (tribbles pseudokinase 1) Show summary »« Hide summary More detailed page go icon to follow link

Target Id	2249
Nomenclature	tribbles pseudokinase 1
Common abbreviation	TRB1
Previous and unofficial names	G-protein-coupled receptor induced protein GIG2 \| TRB1 \| tribbles homolog 1 (Drosophila)
Genes	TRIB1 (Hs), Trib1 (Mm), Trib1 (Rn)
Ensembl ID	ENSG00000173334 (Hs), ENSMUSG00000032501 (Mm), ENSRNOG00000004100 (Rn)
UniProtKB AC	Q96RU8 (Hs), Q8K4K4 (Mm)

TRB2 (tribbles pseudokinase 2) Show summary »« Hide summary More detailed page go icon to follow link

TRB3 (tribbles pseudokinase 3) Show summary »« Hide summary More detailed page go icon to follow link

Target Id	2251
Nomenclature	tribbles pseudokinase 3
Common abbreviation	TRB3
Previous and unofficial names	Neuronal cell death Inducible Putative Kinase \| NIPK \| SKIP3 \| tribbles homolog 3 (Drosophila)
Genes	TRIB3 (Hs), Trib3 (Mm), Trib3 (Rn)
Ensembl ID	ENSG00000101255 (Hs), ENSMUSG00000032715 (Mm), ENSRNOG00000007319 (Rn)
UniProtKB AC	Q96RU7 (Hs), Q8K4K2 (Mm), Q9WTQ6 (Rn)

How to cite this family page

Database page citation:

Trbl family. Accessed on 15/08/2026. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=635.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Gibb AJ, Kelly E, Mathie AA, Peach CJ, Veale EL, Armstrong JF, Faccenda E, Harding SD, Southan C, Davies JA et al. (2025) The Concise Guide to PHARMACOLOGY 2025/26: Enzymes. Br J Pharmacol. 182: S307-S403.