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Melatonin receptors C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).


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Melatonin receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Melatonin Receptors [6]) are activated by the endogenous ligands melatonin and clinically used drugs like ramelteon, agomelatine and tasimelteon.


Targets of relevance to immunopharmacology are highlighted in blue

MT1 receptor C Show summary » More detailed page

MT2 receptor C Show summary » More detailed page


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Further reading

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NC-IUPHAR subcommittee and family contributors

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How to cite this family page

Database page citation:

Ralf Jockers, Daniel P. Cardinali, Philippe Delagrange, Margarita L. Dubocovich, Diana N. Krause, Regina Pekelmann Markus, James Olcese, Jesús Pintor, Nicolas Renault, David Sugden, Gianluca Tosini, Darius Paul Zlotos. Melatonin receptors. Accessed on 23/08/2019. IUPHAR/BPS Guide to PHARMACOLOGY,

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Christopoulos A, Davenport AP, Kelly E, Marrion NV, Peters JA, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. (2017) The Concise Guide to PHARMACOLOGY 2017/18: G protein-coupled receptors. Br J Pharmacol. 174 Suppl 1: S17-S129.