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Protein kinase G (PKG) family

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).


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Cyclic GMP-dependent protein kinase is a dimeric enzyme activated by cyclic GMP generated by particulate guanylyl cyclases or soluble guanylyl cyclases.


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Targets of relevance to immunopharmacology are highlighted in blue

PKG1 (Protein kinase G (PKG) 1) Show summary » More detailed page go icon to follow link

PKG2 (Protein kinase G (PKG) 2) Show summary » More detailed page go icon to follow link


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How to cite this family page

Database page citation:

Protein kinase G (PKG) family. Accessed on 04/12/2021. IUPHAR/BPS Guide to PHARMACOLOGY,

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. (2019) The Concise Guide to PHARMACOLOGY 2019/20: Enzymes. Br J Pharmacol. 176 Issue S1: S297-S396.