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Mitochondrial uncoupling proteins C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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Mitochondrial uncoupling proteins allow dissipation of the mitochondrial proton gradient associated with thermogenesis and regulation of radical formation.

Transporters

Targets of relevance to immunopharmacology are highlighted in blue

UCP1 (Uncoupling protein 1 / SLC25A7) C Show summary »

UCP2 (Uncoupling protein 2 / SLC25A8) C Show summary »

UCP3 (Uncoupling protein 3 / SLC25A9) C Show summary »

UCP4 (Uncoupling protein 4 / SLC25A27) C Show summary »

UCP5 (Uncoupling protein 5 / SLC25A14) C Show summary »

KMCP1 / SLC25A30 C Show summary »

How to cite this family page

Database page citation:

Mitochondrial uncoupling proteins. Accessed on 25/04/2019. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=207.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Kelly E, Marrion NV, Peters JA, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. (2017) The Concise Guide to PHARMACOLOGY 2017/18: Transporters. Br J Pharmacol. 174 Suppl 1: S360-S446.