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Mitochondrial uncoupling proteins C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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Mitochondrial uncoupling proteins allow dissipation of the mitochondrial proton gradient associated with thermogenesis and regulation of radical formation.

Transporters

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Targets of relevance to immunopharmacology are highlighted in blue

UCP1 (Uncoupling protein 1 / SLC25A7) C Show summary »

UCP2 (Uncoupling protein 2 / SLC25A8) C Show summary »

UCP3 (Uncoupling protein 3 / SLC25A9) C Show summary »

UCP4 (Uncoupling protein 4 / SLC25A27) C Show summary »

UCP5 (Uncoupling protein 5 / SLC25A14) C Show summary »

KMCP1 / SLC25A30 C Show summary »

How to cite this family page

Database page citation:

Mitochondrial uncoupling proteins. Accessed on 09/11/2024. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=207.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Transporters. Br J Pharmacol. 180 Suppl 2:S374-469.