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Vesicular glutamate transporters (VGLUTs) C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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Vesicular glutamate transporters (VGLUTs) allow accumulation of glutamate into synaptic vesicles, as well as secretory vesicles in endocrine tissues. The roles of VGLUTs in kidney and liver are unclear. These transporters appear to utilize the proton gradient and also express a chloride conductance [1].

Transporters

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Targets of relevance to immunopharmacology are highlighted in blue

VGLUT1 (Vesicular glutamate transporter 1 / SLC17A7) C Show summary »

VGLUT2 (Vesicular glutamate transporter 2 / SLC17A6) C Show summary »

VGLUT3 (Vesicular glutamate transporter 3 / SLC17A8) C Show summary »

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How to cite this family page

Database page citation:

Vesicular glutamate transporters (VGLUTs). Accessed on 28/11/2022. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=191.

Concise Guide to PHARMACOLOGY citation:

Alexander SP, Kelly E, Mathie A, Peters JA, Veale EL et al. (2021) THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Transporters. Br J Pharmacol. 178 Suppl 1:S412-S513.