Proton-coupled inositol transporter | Transporters | IUPHAR/BPS Guide to IMMUNOPHARMACOLOGY

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SLC superfamily of solute carriers
SLC2 family of hexose and sugar alcohol transporters
Proton-coupled inositol transporter

Proton-coupled inositol transporter C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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Proton-coupled inositol transporters are expressed predominantly in the brain and can be inhibited by phloretin and cytochalasin B [2].

Transporters

Targets of relevance to immunopharmacology are highlighted in blue

HMIT (Proton myo-inositol cotransporter / SLC2A13) C Show summary »« Hide summary

Target Id

888

Nomenclature

Proton myo-inositol cotransporter

Systematic nomenclature

SLC2A13

Common abbreviation

HMIT

Previous and unofficial names

Genes

SLC2A13 (Hs), Slc2a13 (Mm), Slc2a13 (Rn)

Ensembl ID

ENSG00000151229 (Hs), ENSMUSG00000036298 (Mm), ENSRNOG00000015741 (Rn)

UniProtKB AC

Q96QE2 (Hs), Q3UHK1 (Mm), Q921A2 (Rn)

Bioparadigms SLC Tables

SLC2A13 (Hs)

RESOLUTE

SLC2A13 (Hs)

Substrates

myo-inositol [2]

D-chiro-inositol [2]

muco-inositol [2]

scyllo-inositol [2]

Stoichiometry

1 H⁺ : 1 inositol (in) [1]

References

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How to cite this family page

Database page citation:

Proton-coupled inositol transporter. Accessed on 19/04/2024. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=167.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Transporters. Br J Pharmacol. 180 Suppl 2:S374-469.