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DNA polymerases

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).


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DNA polymerases (or DNA-directed DNA polymerases) are enzymes that catalyse the addition of deoxyribonucleotides to replicating DNA strands and they play crucial roles in the processes that repair different types of DNA damage.


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Targets of relevance to immunopharmacology are highlighted in blue

DNA polymerase beta Show summary »

DNA polymerase theta Show summary »


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How to cite this family page

Database page citation:

DNA polymerases. Accessed on 25/07/2024. IUPHAR/BPS Guide to PHARMACOLOGY,

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Enzymes. Br J Pharmacol. 180 Suppl 2:S289-373.