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Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).
Tetraspanins are a superfamily conserved membrane proteins with four transmembrane spanning domains [2,6], with 33 tetraspanin genes identified in the human genome. They are considered to be modulators (or facilitators) of cellular signalling and play significant roles in multiple biological processes [4].
CD37 (CD37 molecule)
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Database page citation:
Tetraspanins. Accessed on 04/12/2023. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=1047.
Concise Guide to PHARMACOLOGY citation:
Alexander SP, Kelly E, Mathie A, Peters JA, Veale EL et al. (2021) THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Introduction and Other Protein Targets. Br J Pharmacol. 178 Suppl 1:S1-S26.