Top ▲

Mitofusin proteins

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).


Click here for help

« Hide

The mitofusins (MFNs) are mitochondrial GTPases that are essential for regulating mitochondrial clustering and fusion [3]. Defects in MFN protein function are associated with mitochondrial diseases.


Click here for help

Targets of relevance to immunopharmacology are highlighted in blue

mitofusin 1 Show summary »

mitofusin 2 Show summary »


Click here for help

Show »

How to cite this family page

Database page citation:

Mitofusin proteins. Accessed on 25/07/2024. IUPHAR/BPS Guide to PHARMACOLOGY,

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Enzymes. Br J Pharmacol. 180 Suppl 2:S289-373.