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Mitofusin proteins

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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The mitofusins (MFNs) are mitochondrial GTPases that are essential for regulating mitochondrial clustering and fusion [3]. Defects in MFN protein function are associated with mitochondrial diseases.

Enzymes

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Targets of relevance to immunopharmacology are highlighted in blue

mitofusin 1 Show summary »

mitofusin 2 Show summary »

References

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How to cite this family page

Database page citation:

Mitofusin proteins. Accessed on 04/10/2022. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=1038.

Concise Guide to PHARMACOLOGY citation:

Alexander SP, Fabbro D, Kelly E, Mathie A, Peters JA, Veale EL et al. (2021) THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Enzymes. Br J Pharmacol. 178 Suppl 1:S313-S411.