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Paraoxonase (PON) family C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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Paraoxonases (PON) are calcium-dependent esterases, which may be involved in lipoprotein turnover and the conversion of lactone statin prodrugs, as well as being targets of organophosphates, such as the insecticide paraoxon.

Enzymes

Targets of relevance to immunopharmacology are highlighted in blue

PON1 (paraoxonase 1) C Show summary »

PON2 (paraoxonase 2) C Show summary »

PON3 (paraoxonase 3) C Show summary »

Further reading

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References

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How to cite this family page

Database page citation:

Paraoxonase (PON) family. Accessed on 17/10/2019. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=1018.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Marrion NV, Peters JA, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. (2017) The Concise Guide to PHARMACOLOGY 2017/18: Enzymes. Br J Pharmacol. 174 Suppl 1: S272-S359.