SLC60 Glucose transporters | Transporters | IUPHAR/BPS Guide to IMMUNOPHARMACOLOGY

SLC60 Glucose transporters C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Transporters

Targets of relevance to immunopharmacology are highlighted in blue

major facilitator superfamily domain containing 4A / SLC60A1 C Show summary »« Hide summary

major facilitator superfamily domain containing 4B / SLC60A2 C Show summary »« Hide summary

Target Id

3044

Nomenclature

major facilitator superfamily domain containing 4B

Systematic nomenclature

SLC60A2

Previous and unofficial names

Mfsd4b | KIAA1919 | NAGLT1

Genes

MFSD4B (Hs), Mfsd4b1 (Mm), Mfsd4b1 (Rn)

Ensembl ID

ENSG00000173214 (Hs), ENSMUSG00000038522 (Mm), ENSRNOG00000024543 (Rn)

UniProtKB AC

Q5TF39 (Hs), Q8VCV9 (Mm)

RESOLUTE

MFSD4B (Hs)

Transport type (Rat)

Co-transporter / Na⁺ (1:1) uptake [1]

Substrates

α-Me-glucose, D-glucose Rat [1]

Inhibitors

phloretin [1] - Rat

urea [2] - Rat

phlorizin [1] - Rat

Comment

Expressed in rat kidney (cortex and medulla), brain, liver and lung [1].

References

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How to cite this family page

Database page citation:

SLC60 Glucose transporters. Accessed on 14/10/2024. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=1012.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Transporters. Br J Pharmacol. 180 Suppl 2:S374-469.

SLC60 Glucose transporters C

Transporters

Targets of relevance to immunopharmacology are highlighted in blue

Further reading

References

How to cite this family page