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Adipo1 receptor

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Target not currently curated in GtoImmuPdb

Target id: 649

Nomenclature: Adipo1 receptor

Family: Adiponectin receptors

Contents:

Gene and Protein Information Click here for help
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human 7 375 1q32.1 ADIPOR1 adiponectin receptor 1
Mouse 7 375 1 E4 Adipor1 adiponectin receptor 1
Rat - - 13q13 Adipor1 adiponectin receptor 1
Previous and Unofficial Names Click here for help
ACDCR1 | CGI45 | PAQR1 | progestin and adipoQ receptor family member I
Database Links Click here for help
Alphafold Q96A54 (Hs), Q91VH1 (Mm)
ChEMBL Target CHEMBL3392946 (Hs)
Ensembl Gene ENSG00000159346 (Hs), ENSMUSG00000026457 (Mm), ENSRNOG00000004143 (Rn)
Human Protein Atlas ENSG00000159346 (Hs)
OMIM 607945 (Hs)
Pharos Q96A54 (Hs)
UniProtKB Q96A54 (Hs), Q91VH1 (Mm)
Wikipedia ADIPOR1 (Hs)
Selected 3D Structures Click here for help
Image of receptor 3D structure from RCSB PDB
Description:  Crystal structure of the human adiponectin receptor 1
PDB Id:  3WXV
Resolution:  2.9Å
Species:  Human
References:  1
Natural/Endogenous Ligands Click here for help
adiponectin {Sp: Human}
globular adiponectin {Sp: Human}
Rank order of potency (Human)
globular adiponectin (ADIPOQ, Q15848) > adiponectin (ADIPOQ, Q15848)
Immuno Process Associations
Immuno Process:  Cytokine production & signalling

References

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1. Tanabe H, Fujii Y, Okada-Iwabu M, Iwabu M, Nakamura Y, Hosaka T, Motoyama K, Ikeda M, Wakiyama M, Terada T et al.. (2015) Crystal structures of the human adiponectin receptors. Nature, 520 (7547): 312-6. [PMID:25855295]

How to cite this page

Adiponectin receptors: Adipo1 receptor. Last modified on 05/12/2017. Accessed on 20/04/2024. IUPHAR/BPS Guide to PHARMACOLOGY, https://www.guidetoimmunopharmacology.org/GRAC/ObjectDisplayForward?objectId=649.