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sodium/potassium-transporting ATPase subunit γ

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Target not currently curated in GtoImmuPdb

Target id: 2610

Nomenclature: sodium/potassium-transporting ATPase subunit γ

Family: Na+/K+-ATPases

Gene and Protein Information Click here for help
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human 1 66 11q23.3 FXYD2 FXYD domain containing ion transport regulator 2
Mouse 1 70 9 A5.2 Fxyd2 FXYD domain-containing ion transport regulator 2
Rat 1 66 8q22 Fxyd2 FXYD domain-containing ion transport regulator 2
Previous and Unofficial Names Click here for help
sodium pump gamma chain | Na(+)/K(+) ATPase subunit gamma
Database Links Click here for help
ChEMBL Target
DrugBank Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Gene
OMIM
Orphanet
Pharos
RefSeq Nucleotide
RefSeq Protein
UniProtKB
Wikipedia
Clinically-Relevant Mutations and Pathophysiology Click here for help
Disease:  Hypomagnesemia 2, renal; HOMG2
Synonyms: Autosomal dominant primary hypomagnesemia with hypocalciuria [Orphanet: ORPHA34528]
OMIM: 154020
Orphanet: ORPHA34528
References:  1

References

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1. Meij IC, Koenderink JB, De Jong JC, De Pont JJ, Monnens LA, Van Den Heuvel LP, Knoers NV. (2003) Dominant isolated renal magnesium loss is caused by misrouting of the Na+,K+-ATPase gamma-subunit. Ann N Y Acad Sci, 986: 437-43. [PMID:12763862]

How to cite this page

Na+/K+-ATPases: sodium/potassium-transporting ATPase subunit γ. Last modified on 05/10/2020. Accessed on 16/06/2021. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetoimmunopharmacology.org/GRAC/ObjectDisplayForward?objectId=2610.