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Target has curated data in GtoImmuPdb
Target id: 2309
Nomenclature: Granulocyte macrophage colony-stimulating factor receptor
Family: IL-3 receptor family
Quaternary Structure: Subunits |
GM-CSF receptor, α subunit (Ligand-binding subunit) |
Cytokine receptor common β subunit (Other subunit) |
Previous and Unofficial Names |
GM-CSF receptor |
Natural/Endogenous Ligands |
G-CSF {Sp: Human} |
GM-CSF {Sp: Human} |
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Immunopharmacology Comments |
The functional GM-CSF receptor is a heterodimer consisting of the ligand binding GM-CSF receptor α subunit (CSF2RA) and CSF2RB (cytokine receptor common β subunit). CSF2RB is required for the formation of the functional receptors for IL-3, IL-5 and GM-CSF. |
IL-3 receptor family: Granulocyte macrophage colony-stimulating factor receptor. Last modified on 22/03/2017. Accessed on 06/12/2024. IUPHAR/BPS Guide to PHARMACOLOGY, https://www.guidetoimmunopharmacology.org/GRAC/ObjectDisplayForward?objectId=2309.