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Target not currently curated in GtoImmuPdb
Target id: 1996
Nomenclature: casein kinase 1 alpha 1 like
Abbreviated Name: CK1-A2
Family: Casein kinase 1 (CK1) family
Gene and Protein Information | ||||||
Species | TM | AA | Chromosomal Location | Gene Symbol | Gene Name | Reference |
Human | - | 337 | 13q13.3 | CSNK1A1L | casein kinase 1 alpha 1 like |
Previous and Unofficial Names |
CKI-alpha-like | casein kinase 1, alpha 1-like |
Database Links | |
Alphafold | Q8N752 (Hs) |
BRENDA | 2.7.11.1 |
ChEMBL Target | CHEMBL5520 (Hs) |
Ensembl Gene | ENSG00000180138 (Hs) |
Entrez Gene | 122011 (Hs) |
Human Protein Atlas | ENSG00000180138 (Hs) |
KEGG Enzyme | 2.7.11.1 |
KEGG Gene | hsa:122011 (Hs) |
Pharos | Q8N752 (Hs) |
RefSeq Nucleotide | NM_145203 (Hs) |
RefSeq Protein | NP_660204 (Hs) |
UniProtKB | Q8N752 (Hs) |
Wikipedia | CSNK1A1L (Hs) |
Enzyme Reaction | ||||
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DiscoveRx KINOMEscan® screen | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
A screen of 72 inhibitors against 456 human kinases. Quantitative data were derived using DiscoveRx KINOMEscan® platform. http://www.discoverx.com/services/drug-discovery-development-services/kinase-profiling/kinomescan Reference: 1-2 |
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Key to terms and symbols | Click column headers to sort | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Target used in screen: CSNK1A1L | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Displaying the top 10 most potent ligands View all ligands in screen » |
1. Davis MI, Hunt JP, Herrgard S, Ciceri P, Wodicka LM, Pallares G, Hocker M, Treiber DK, Zarrinkar PP. (2011) Comprehensive analysis of kinase inhibitor selectivity. Nat Biotechnol, 29 (11): 1046-51. [PMID:22037378]
2. Wodicka LM, Ciceri P, Davis MI, Hunt JP, Floyd M, Salerno S, Hua XH, Ford JM, Armstrong RC, Zarrinkar PP et al.. (2010) Activation state-dependent binding of small molecule kinase inhibitors: structural insights from biochemistry. Chem Biol, 17 (11): 1241-9. [PMID:21095574]
Casein kinase 1 (CK1) family: casein kinase 1 alpha 1 like. Last modified on 29/01/2016. Accessed on 04/12/2024. IUPHAR/BPS Guide to PHARMACOLOGY, https://www.guidetoimmunopharmacology.org/GRAC/ObjectDisplayForward?objectId=1996.