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Contents:
| Quaternary Structure: Complexes |
| Interleukin-22α1/20β heteromer |
| Interleukin-22α1/10β heteromer |
Gene and Protein Information  |
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| Species | TM | AA | Chromosomal Location | Gene Symbol | Gene Name | Reference |
| Human | 1 | 574 | 1p36.11 | IL22RA1 | interleukin 22 receptor subunit alpha 1 | |
| Mouse | 1 | 581 | 4 67.99 cM | Il22ra1 | interleukin 22 receptor, alpha 1 | |
| Rat | - | - | Il22ra1 | interleukin 22 receptor subunit alpha 1 | ||
| Previous and Unofficial Names |
| CRF2-9 | IL22R | interleukin-22 receptor subunit alpha-1 | interleukin 22 receptor, alpha 1 |
| Database Links |
|
| Alphafold | Q8N6P7 (Hs), Q80XZ4 (Mm) |
| CATH/Gene3D | 2.60.40.10 |
| ChEMBL Target | CHEMBL4804251 (Hs) |
| Ensembl Gene | ENSG00000142677 (Hs), ENSMUSG00000037157 (Mm), ENSRNOG00000066331 (Rn) |
| Entrez Gene | 58985 (Hs), 230828 (Mm), 362629 (Rn) |
| Human Protein Atlas | ENSG00000142677 (Hs) |
| KEGG Gene | hsa:58985 (Hs), mmu:230828 (Mm), rno:362629 (Rn) |
| OMIM | 605457 (Hs) |
| Pharos | Q8N6P7 (Hs) |
| UniProtKB | Q8N6P7 (Hs), Q80XZ4 (Mm) |
| Wikipedia | IL22RA1 (Hs) |
| Immunopharmacology Comments |
| IL22RA1 is a subunit in the heterodimeric receptors for interleukins 20 and 24 (which bind to the interleukin-22α1/20β heteromer) and IL-22 (which binds to the interleukin-22α1/10β heteromer). |
How to cite this page
IL-10 receptor family: Interleukin 22 receptor, α1 subunit. Last modified on 06/04/2017. Accessed on 04/11/2025. IUPHAR/BPS Guide to PHARMACOLOGY, https://www.guidetoimmunopharmacology.org/GRAC/ObjectDisplayForward?objectId=1731.
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