SAR-20347

Ligand id: 9803

Name: SAR-20347

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 6
Topological polar surface area 110.69
Molecular weight 444.1
XLogP 3.08
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Comments
SAR-20347 is an experimental small molecule Janus kinase 1 (JAK1)/ tyrosine kinase 2 (TYK2) inhibitor [2]. It has anti-inflammatory potential, via inhibition of Th17 proinflammatory cytokine production (e.g. IL-22 and IL-23) and signaling.
Database Links
CAS Registry No. 1450881-55-6 (source: PubChem)
GtoPdb PubChem SID 354702275
PubChem CID 71727668
Search Google for chemical match using the InChIKey HEDPDFHTQKEORT-UHFFFAOYSA-N
Search Google for chemicals with the same backbone HEDPDFHTQKEORT
Search UniChem for chemical match using the InChIKey HEDPDFHTQKEORT-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone HEDPDFHTQKEORT