apraclonidine   Click here for help

GtoPdb Ligand ID: 7117

Synonyms: AL-02145 | Iopidine® | para-amino clonidine
Approved drug
apraclonidine is an approved drug (FDA (1987))
Compound class: Synthetic organic
Comment: Apraclonidine (para-amino clonidine) is a clonidine derivative which acts as sympathomimetic α2-adrenoceptor agonist.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 2
Topological polar surface area 62.44
Molecular weight 244.03
XLogP 1.86
No. Lipinski's rules broken 0
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Canonical SMILES Nc1cc(Cl)c(c(c1)Cl)NC1=NCCN1
Isomeric SMILES Nc1cc(Cl)c(c(c1)Cl)NC1=NCCN1
InChI InChI=1S/C9H10Cl2N4/c10-6-3-5(12)4-7(11)8(6)15-9-13-1-2-14-9/h3-4H,1-2,12H2,(H2,13,14,15)
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (1987))
IUPAC Name Click here for help
International Nonproprietary Names Click here for help
INN number INN
6263 apraclonidine
Synonyms Click here for help
AL-02145 | Iopidine® | para-amino clonidine
Database Links Click here for help
Specialist databases
GPCRdb Ligand apraclonidine
Other databases
CAS Registry No. 66711-21-5
DrugBank Ligand DB00964
DrugCentral Ligand 229
GtoPdb PubChem SID 178103694
PubChem CID 2216
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Wikipedia Apraclonidine