hydromorphone   Click here for help

GtoPdb Ligand ID: 7082

Synonyms: Dilaudid® | hydromorphone hydrochloride | Palladone®
Approved drug
hydromorphone is an approved drug (FDA (1984))
Compound class: Synthetic organic
Comment: Hydromorphone is a semi-synthetic opioid receptor agonist.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 0
Topological polar surface area 49.77
Molecular weight 285.14
XLogP 0.6
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
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Canonical SMILES O=C1CCC2C34C1Oc1c4c(CC2N(CC3)C)ccc1O
Isomeric SMILES O=C1CC[C@@H]2[C@@]34[C@H]1Oc1c4c(C[C@H]2N(CC3)C)ccc1O
InChI InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2,4,10-11,16,19H,3,5-8H2,1H3/t10-,11+,16-,17-/m0/s1
InChI Key WVLOADHCBXTIJK-YNHQPCIGSA-N
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (1984))
IUPAC Name Click here for help
(4R,4aR,7aR,12bS)-9-hydroxy-3-methyl-1,2,4,4a,5,6,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one
International Nonproprietary Names Click here for help
INN number INN
1770 hydromorphone
Synonyms Click here for help
Dilaudid® | hydromorphone hydrochloride | Palladone®
Database Links Click here for help
Specialist databases
GPCRdb Ligand hydromorphone
Other databases
CAS Registry No. 466-99-9
ChEBI CHEBI:5790
ChEMBL Ligand CHEMBL398707
DrugBank Ligand DB00327
DrugCentral Ligand 1393
GtoPdb PubChem SID 178103661
PubChem CID 5284570
Search Google for chemical match using the InChIKey WVLOADHCBXTIJK-YNHQPCIGSA-N
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UniChem Compound Search for chemical match using the InChIKey WVLOADHCBXTIJK-YNHQPCIGSA-N
UniChem Connectivity Search for chemical match using the InChIKey WVLOADHCBXTIJK-YNHQPCIGSA-N
Wikipedia Hydromorphone