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evodenoson   Click here for help

GtoPdb Ligand ID: 5594

Synonyms: ATL 313 | ATL-313
Compound class: Synthetic organic

evodenoson is commercially available from our sponsors

2D Structure
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2D Structure

An image of the ligand's 2D structure. For small molecules with SMILES these are drawn using the NCI/CADD Chemical Identifier Resolver. Click on the image to access the chemical structure search tool with the ligand pre-loaded in the structure editor. For other types of ligands, e.g. longer nucleotides and peptides, a manually drawn representation of the molecule may be provided.

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Physico-chemical Properties
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Physico-chemical Properties

Calculated molecular properties are available for small molecules and natural products (not peptides). Properties were generated using the Chemistry Development Kit (CDK) (Willighagen EL et al. Journal of Cheminformatics vol. 9:33. 2017, doi:10.1186/s13321-017-0220-4; https://cdk.github.io/). All properties were selected to enable the prediction of the Lipinski Rule-of-Five profile or ‘druglikeness’ for each ligand. For more info on each category see the help pages.

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Hydrogen bond acceptors 12
Hydrogen bond donors 4
Rotatable bonds 7
Topological polar surface area 177.95
Molecular weight 499.22
XLogP 0.64
No. Lipinski's rules broken 1

Generated using the Chemistry Development Kit (CDK) (Willighagen EL et al. Journal of Cheminformatics vol. 9:33. 2017, doi:10.1186/s13321-017-0220-4; https://cdk.github.io/)
SMILES / InChI / InChIKey
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SMILES / InChI / InChIKey

SMILES (Simplified Molecular Input Line Entry Specification) A specification for unambiguously describing the structure of chemical molecules using short ASCII strings. Canonical SMILES specify a unique representation of the 2D structure without chiral or isotopic specifications. Isomeric SMILES include chiral specification and isotopes.

Standard InChI (IUPAC International Chemical Identifier) and InChIKey InChI is a non-proprietary, standard, textual identifier for chemical substances designed to facilitate linking of information and database searching. An InChIKey is a simplified version of a full InChI, designed for easier web searching.

Generated using the Chemistry Development Kit (CDK) (Willighagen EL et al. Journal of Cheminformatics vol. 9:33. 2017, doi:10.1186/s13321-017-0220-4; https://cdk.github.io/)

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Canonical SMILES COC(=O)N1CCC(CC1)CC#Cc1nc(N)c2c(n1)n(cn2)C1OC(C(C1O)O)C(=O)NC1CC1
Isomeric SMILES COC(=O)N1CCC(CC1)CC#Cc1nc(N)c2c(n1)n(cn2)[C@@H]1O[C@@H]([C@H]([C@H]1O)O)C(=O)NC1CC1
InChI InChI=1S/C23H29N7O6/c1-35-23(34)29-9-7-12(8-10-29)3-2-4-14-27-19(24)15-20(28-14)30(11-25-15)22-17(32)16(31)18(36-22)21(33)26-13-5-6-13/h11-13,16-18,22,31-32H,3,5-10H2,1H3,(H,26,33)(H2,24,27,28)/t16-,17+,18-,22+/m0/s1
InChI Key SQJXTUJMBYVDBB-RQXXJAGISA-N

Generated using the Chemistry Development Kit (CDK) (Willighagen EL et al. Journal of Cheminformatics vol. 9:33. 2017, doi:10.1186/s13321-017-0220-4; https://cdk.github.io/)
Classification Click here for help
Compound class Synthetic organic
IUPAC Name Click here for help
methyl 4-[3-[6-amino-9-[(2R,3R,4S,5S)-5-(cyclopropylcarbamoyl)-3,4-dihydroxyoxolan-2-yl]purin-2-yl]prop-2-ynyl]piperidine-1-carboxylate
International Nonproprietary Names Click here for help
INN number INN
9675 evodenoson
Synonyms Click here for help
ATL 313 | ATL-313
Database Links Click here for help
CAS Registry No. 844873-47-8 (source: Scifinder)
ChEMBL Ligand CHEMBL1950651
GtoPdb PubChem SID 178102229
PubChem CID 11627443
Search Google for chemical match using the InChIKey SQJXTUJMBYVDBB-RQXXJAGISA-N
Search Google for chemicals with the same backbone SQJXTUJMBYVDBB
Search PubMed clinical trials evodenoson
Search PubMed titles evodenoson
Search PubMed titles/abstracts evodenoson
UniChem Compound Search for chemical match using the InChIKey SQJXTUJMBYVDBB-RQXXJAGISA-N
UniChem Connectivity Search for chemical match using the InChIKey SQJXTUJMBYVDBB-RQXXJAGISA-N

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MedChemExpress
Evodenoson (links to external site)
Cat. No. HY-105017