guanabenz   Click here for help

GtoPdb Ligand ID: 5443

Abbreviated name: GBZ
Synonyms: NSC 68982 | Wy 8678 | Wytensin®
Approved drug
guanabenz is an approved drug (FDA (1982))
Compound class: Synthetic organic
Comment: Guanabenz is an antihypertensive drug.
Marketed formulations may contain guanabenz acetate (PubChem CID 5702062). This entry shows the E isomer, as represented in the INN record for guanabenz.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 2
Topological polar surface area 76.76
Molecular weight 230.01
XLogP 3.21
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
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Canonical SMILES NC(=N/N=C\c1c(Cl)cccc1Cl)N
Isomeric SMILES NC(=N/N=C\c1c(Cl)cccc1Cl)N
InChI InChI=1S/C8H8Cl2N4/c9-6-2-1-3-7(10)5(6)4-13-14-8(11)12/h1-4H,(H4,11,12,14)/b13-4-
InChI Key WDZVGELJXXEGPV-PQMHYQBVSA-N
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (1982))
International Nonproprietary Names Click here for help
INN number INN
3108 guanabenz
Synonyms Click here for help
NSC 68982 | Wy 8678 | Wytensin®
Database Links Click here for help
ChEMBL Ligand CHEMBL1331786
DrugCentral Ligand 3952
GtoPdb PubChem SID 178102094
PubChem CID 5353646
Search Google for chemical match using the InChIKey WDZVGELJXXEGPV-PQMHYQBVSA-N
Search Google for chemicals with the same backbone WDZVGELJXXEGPV
Search PubMed clinical trials guanabenz
Search PubMed titles guanabenz
Search PubMed titles/abstracts guanabenz
UniChem Compound Search for chemical match using the InChIKey WDZVGELJXXEGPV-PQMHYQBVSA-N
UniChem Connectivity Search for chemical match using the InChIKey WDZVGELJXXEGPV-PQMHYQBVSA-N
Wikipedia Guanabenz