Rolipram is a a well-characterized PDE4 inhibitor that has been widely used in research to examine the role(s) played by PDE4 in autoimmune and inflammatory diseases [2-3
], Alzheimer's disease [1
] and cognition [4
]. The INN-assigned preparation of rolipram is a racemic mixture of R
-rolipram and S
-rolipram. The structure shown here does not specify stereochemistry to represent the mixture. The two stereoisomers are represented on PubChem by CID 448055
and CID 158758
, and by the entries on DrugBank linked to in the table above.