GtoPdb is requesting financial support from commercial users. Please see our sustainability page for more information.

G-CSF   Click here for help

GtoPdb Ligand ID: 4934

Synonyms: Granocyte®
Approved drug Immunopharmacology Ligand
G-CSF is an approved drug
Compound class: Endogenous peptide in human, mouse or rat
Comment: Lenograstim is a recombinant form of glycosylated granulocyte colony-stimulating factor, with exactly the same sequence and function as the endogenous peptide.
Species: Human
Peptide Sequence Click here for help
ATPLGPASSLPQSFLLKCLEQVRKIQGDGAALQEKLVSECATYKLCHPEELVLLGHSLGIPWAPLSSCPSQALQLAGCLS
QLHSGLFLYQGLLQALEGISPELGPTLDTLQLDVADFATTIWQQMEELGMAPALQPTQGAMPAFASAFQRRAGGVLVASH
LQSFLEVSYRVLRHLAQP
Selected 3D Structures
PDB Id: 1RHG
Image of ligand 3D structure from RCSB PDB
Post-translational Modification
Predicted O-linked glycosylation of threonine at position 137; disulphide bond formation between cysteine residues at positions 40 and 46, and 68 and 78