furosemide

Ligand id: 4839

Name: furosemide

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Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 3
Rotatable bonds 5
Topological polar surface area 131.01
Molecular weight 330.01
XLogP 1.2
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1966))
WHO Essential Medicine WHO Model List of Essential Medicines (21st List, 2019). Access PDF version.
IUPAC Name
4-chloro-2-[(furan-2-ylmethyl)amino]-5-sulfamoylbenzoic acid
International Nonproprietary Names
INN number INN
1584 furosemide
Synonyms
dihydroflumethiazide | frusemide | Lasix® | methforylthiazidine
Comments
Furosemide is a loop diuretic drug.
Database Links
CAS Registry No. 54-31-9 (source: Scifinder)
ChEBI CHEBI:47426
ChEMBL Ligand CHEMBL35
DrugBank Ligand DB00695
GtoPdb PubChem SID 178101541
PubChem CID 3440
RCSB PDB Ligand FUN
Search Google for chemical match using the InChIKey ZZUFCTLCJUWOSV-UHFFFAOYSA-N
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Search UniChem for chemical match using the InChIKey ZZUFCTLCJUWOSV-UHFFFAOYSA-N
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Wikipedia Furosemide

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Tocris
Furosemide
Cat. No. 3109