Abbreviated name: NDGA
Synonyms: Actinex®
nordihydroguiaretic acid is an approved drug (FDA (1992))
Compound class:
Natural product
Comment: Although we show the non-isomeric molecule, the approved drug masoprocol is a specific stereoisomer of NGDA, with IUPAC name 4-[(2S,3R)-4-(3,4-dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol (as shown in the PubChem record). The ChEMBL record displays the non-stereoisomeric molecule. PubChem lists 6 stereoisomers of this compound.
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Classification ![]() |
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Compound class | Natural product |
Approved drug? | Yes (FDA (1992)) |
Approved drug? | Yes. FDA (1992) |
Withdrawn drug? | Yes |
IUPAC Name ![]() |
4-[4-(3,4-dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol |
International Nonproprietary Names ![]() |
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INN number | INN |
6615 | masoprocol |
Synonyms ![]() |
Actinex® |
Database Links ![]() |
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CAS Registry No. | 500-38-9 (source: Scifinder) |
ChEMBL Ligand | CHEMBL52 |
DrugBank Ligand | DB00179 |
GtoPdb PubChem SID | 178101082 |
PubChem CID | 4534 |
Search Google for chemical match using the InChIKey | HCZKYJDFEPMADG-UHFFFAOYSA-N |
Search Google for chemicals with the same backbone | HCZKYJDFEPMADG |
Search PubMed clinical trials | masoprocol |
Search PubMed titles | masoprocol |
Search PubMed titles/abstracts | masoprocol |
UniChem Compound Search for chemical match using the InChIKey | HCZKYJDFEPMADG-UHFFFAOYSA-N |
UniChem Connectivity Search for chemical match using the InChIKey | HCZKYJDFEPMADG-UHFFFAOYSA-N |
Wikipedia | Nordihydroguaiaretic_acid, Masoprocol |
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Nordihydroguaiaretic acid (links to external site)
Cat. No. HY-N0198 |