Synonyms: Agilus® | Dantrium® | F-368 | F-440 | Ryanodex®
dantrolene is an approved drug (FDA (1974))
Compound class:
Synthetic organic
Comment: Dantrolene inhibits ryanodine receptor subtypes 1 and 3 (RyR1, and RyR3). The structure of dantrolene is commonly represented in the literature with charges, and it is this structure that we show here and link to in PubChem. However, the FDA and INN documents represent the compound without the charge.
Marketed formulations may contain dantrolene sodium (PubChem CID 6604100). ![]() View more information in the IUPHAR Pharmacology Education Project: dantrolene |
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Classification ![]() |
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Compound class | Synthetic organic |
Approved drug? | Yes (FDA (1974)) |
Approved drug? | Yes. FDA (1974) |
IUPAC Name ![]() |
1-[[5-(4-nitrophenyl)furan-2-yl]methylideneamino]imidazolidine-2,4-dione |
International Nonproprietary Names ![]() |
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INN number | INN |
2317 | dantrolene |
Synonyms ![]() |
Agilus® | Dantrium® | F-368 | F-440 | Ryanodex® |
Database Links ![]() |
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CAS Registry No. | 7261-97-4 (source: Scifinder) |
ChEBI | CHEBI:4317 |
ChEMBL Ligand | CHEMBL1201288 |
DrugBank Ligand | DB01219 |
DrugCentral Ligand | 780 |
GtoPdb PubChem SID | 178100992 |
PubChem CID | 6914273 |
Search Google for chemical match using the InChIKey | OZOMQRBLCMDCEG-VIZOYTHASA-N |
Search Google for chemicals with the same backbone | OZOMQRBLCMDCEG |
Search PubMed clinical trials | dantrolene |
Search PubMed titles | dantrolene |
Search PubMed titles/abstracts | dantrolene |
UniChem Compound Search for chemical match using the InChIKey | OZOMQRBLCMDCEG-VIZOYTHASA-N |
UniChem Connectivity Search for chemical match using the InChIKey | OZOMQRBLCMDCEG-VIZOYTHASA-N |
Wikipedia | Dantrolene |
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Dantrolene (links to external site)
Cat. No. HY-12542 |