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sonelokimab   Click here for help

GtoPdb Ligand ID: 10491

Synonyms: IL17-MS3086 | IL17MS3086 | M-1095 | M1095 | MSB-0010841 | MSB0010841 | SEQ ID 836 [WO2012156219A1]
Immunopharmacology Ligand
Compound class: Antibody
Comment: Sonelokimab (MSB0010841; M1095) is an anti-IL-17A/F single chain camelid nanobody [1]. The peptide sequence for proposed INN sonelokimab is a 100% match for SEQ ID 836 that is claimed in Merck/Ablynx patent WO2012156219A1. Sonelokimab potently binds to both IL-17A and -F and prevents IL-17R pathway activation (e.g . IL-6 production), and was designed for anti-inflammatory potential.
Classification Click here for help
Compound class Antibody
International Nonproprietary Names Click here for help
INN number INN
11137 sonelokimab
Synonyms Click here for help
IL17-MS3086 | IL17MS3086 | M-1095 | M1095 | MSB-0010841 | MSB0010841 | SEQ ID 836 [WO2012156219A1]
Database Links Click here for help
Specialist databases
IMGT/mAb-DB 971
Other databases
GtoPdb PubChem SID 385612250
Search PubMed clinical trials sonelokimab
Search PubMed titles sonelokimab
Search PubMed titles/abstracts sonelokimab