zoligratinib [Ligand Id: 9787] activity data from GtoPdb

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  • platelet derived growth factor receptor beta in Human [GtoPdb: 1804] [UniProtKB: P09619]
Created with Highcharts 10.3.3ValuesChart context menuplatelet derived growth factor receptor betapKd HumanpKi HumanpIC50 HumanpEC50 Human01234567Highcharts.com
  • fibroblast growth factor receptor 1 in Human [GtoPdb: 1808] [UniProtKB: P11362]
Created with Highcharts 10.3.3ValuesChart context menufibroblast growth factor receptor 1pKd HumanpKi HumanpIC50 HumanpEC50 Human0246810Highcharts.com
  • fibroblast growth factor receptor 2 in Human [GtoPdb: 1809] [UniProtKB: P21802]
Created with Highcharts 10.3.3ValuesChart context menufibroblast growth factor receptor 2pKd HumanpKi HumanpIC50 HumanpEC50 Human0246810Highcharts.com
  • fibroblast growth factor receptor 3 in Human [GtoPdb: 1810] [UniProtKB: P22607]
Created with Highcharts 10.3.3ValuesChart context menufibroblast growth factor receptor 3pKd HumanpKi HumanpIC50 HumanpEC50 Human0246810Highcharts.com
  • fibroblast growth factor receptor 4 in Human [GtoPdb: 1811] [UniProtKB: P22455]
Created with Highcharts 10.3.3ValuesChart context menufibroblast growth factor receptor 4pKd HumanpKi HumanpIC50 HumanpEC50 Human02468Highcharts.com
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
platelet derived growth factor receptor beta in Human [GtoPdb: 1804] [UniProtKB: P09619]
GtoPdb - - 6.25 pIC50 560 nM IC50 Mol Cancer Ther (2014) 13: 2547-58 [PMID:25169980]
fibroblast growth factor receptor 1 in Human [GtoPdb: 1808] [UniProtKB: P11362]
GtoPdb - - 8.04 pIC50 9.2 nM IC50 Mol Cancer Ther (2014) 13: 2547-58 [PMID:25169980]
fibroblast growth factor receptor 2 in Human [GtoPdb: 1809] [UniProtKB: P21802]
GtoPdb - - 8.12 pIC50 7.6 nM IC50 Mol Cancer Ther (2014) 13: 2547-58 [PMID:25169980]
fibroblast growth factor receptor 3 in Human [GtoPdb: 1810] [UniProtKB: P22607]
GtoPdb - - 7.66 pIC50 22 nM IC50 Mol Cancer Ther (2014) 13: 2547-58 [PMID:25169980]
fibroblast growth factor receptor 4 in Human [GtoPdb: 1811] [UniProtKB: P22455]
GtoPdb - - 6.54 pIC50 290 nM IC50 Mol Cancer Ther (2014) 13: 2547-58 [PMID:25169980]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.