BRD3444 [Ligand Id: 9648] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL3560390 |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| Plasmodium falciparum phenylalanyl-tRNA synthetase alpha subunit in Plasmodium berghei [GtoPdb: 2954] | ||||||||
| GtoPdb | Parasite liver stage assay | - | 6.85 | pEC50 | 140 | nM | EC50 | Nature (2016) 538: 344-349 [PMID:27602946] |
| Plasmodium falciparum phenylalanyl-tRNA synthetase alpha subunit in Plasmodium falciparum [GtoPdb: 2954] | ||||||||
| GtoPdb | - | - | 7.34 | pIC50 | 46 | nM | IC50 | Nature (2016) 538: 344-349 [PMID:27602946] |
| Plasmodium falciparum phenylalanyl-tRNA synthetase alpha subunit in Plasmodium falciparum 3D7 [GtoPdb: 2954] [UniProtKB: Q8I246] | ||||||||
| GtoPdb | Parasite late stage (IV–V) gametocyte assay | - | 6.18 | pEC50 | 663 | nM | EC50 | Nature (2016) 538: 344-349 [PMID:27602946] |
| Plasmodium falciparum phenylalanyl-tRNA synthetase alpha subunit in Plasmodium falciparum Dd2 [GtoPdb: 2954] | ||||||||
| GtoPdb | Parasite growth inhibition assay | - | 8.05 | pEC50 | 9 | nM | EC50 | Nature (2016) 538: 344-349 [PMID:27602946] |
ChEMBL data shown on this page come from version 34:
Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
