AZ8838 [Ligand Id: 9585] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| PAR2 in Human [GtoPdb: 348] [UniProtKB: P55085] | ||||||||
| GtoPdb | Saturation binding of [3H]-AZ8838 antagonist to wild-type PAR2. | - | 6.46 | pKd | 344 | nM | Kd | Nature (2017) 545: 112-115 [PMID:28445455] |
| GtoPdb | In a FLIPR assay measuring SLIGRL-NH2-induced calcium mobilisation. | - | 5.64 | pIC50 | 2300 | nM | IC50 | Nature (2017) 545: 112-115 [PMID:28445455] |
| GtoPdb | Measuring SLIGRL-NH2-induced IP1 formation | - | 5.82 | pIC50 | 1500 | nM | IC50 | Nature (2017) 545: 112-115 [PMID:28445455] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
