AZ8838 [Ligand Id: 9585] activity data from GtoPdb

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  • PAR2 in Human [GtoPdb: 348] [UniProtKB: P55085]
  • This target only has 0 pki data point
1 _lig_chart_1 PAR2 Human
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
PAR2 in Human [GtoPdb: 348] [UniProtKB: P55085]
GtoPdb Saturation binding of [3H]-AZ8838 antagonist to wild-type PAR2. - 6.46 pKd 344 nM Kd Nature (2017) 545: 112-115 [PMID:28445455]
GtoPdb In a FLIPR assay measuring SLIGRL-NH2-induced calcium mobilisation. - 5.64 pIC50 2300 nM IC50 Nature (2017) 545: 112-115 [PMID:28445455]
GtoPdb Measuring SLIGRL-NH2-induced IP1 formation - 5.82 pIC50 1500 nM IC50 Nature (2017) 545: 112-115 [PMID:28445455]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.